E01¶


Research	R0052 — Methodology Claims
Run	2026-03-31
Claim	C003
Source	SRC02
Evidence	SRC02-E01
Type	Factual

GRADE separates evidence quality from recommendation strength as a core design feature

URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC2335261/

Extract¶

GRADE separates the process of assessing quality of evidence from the process of making recommendations. Judgments about the strength of a recommendation depend on more than just the quality of evidence. Strong recommendations can arise from low-quality evidence, and weak recommendations can arise from high-quality evidence, when other factors (values, resources, feasibility) dominate.

Relevance to Hypotheses¶

Hypothesis	Relationship	Strength
H1	Supports	Directly confirms the claim
H2	Contradicts	No evidence for partial correctness
H3	Contradicts	Definitively refutes material incorrectness

Context¶

Source is authoritative in its domain and directly addresses the specific claim being investigated.