R0052/2026-03-31/C003/SRC01

Research	R0052 — Methodology Claims
Run	2026-03-31
Claim	C003
Search	S01
Result	S01-R01
Source	SRC01

GRADE Handbook

Source

Field	Value
Title	GRADE Handbook
Publisher	GRADEpro
Author(s)	Various
Date	Various
URL	https://gradepro.org/handbook/
Type	Reference handbook

Summary

Dimension	Rating
Reliability	High
Relevance	High
Bias: Missing data	Low risk
Bias: Measurement	N/A
Bias: Selective reporting	Low risk
Bias: Randomization	N/A — not an RCT
Bias: Protocol deviation	N/A — not an RCT
Bias: COI/Funding	Low risk

Rationale

Dimension	Rationale
Reliability	Authoritative source in its domain
Relevance	Directly addresses the claim
Bias flags	No significant bias concerns

Evidence Extracts

Evidence ID	Summary
SRC01-E01	GRADE handbook confirms separation of evidence quality from