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R0023/2026-03-25/Q001/S01/R03

Domain-specific study on chain-of-thought limitations in medical question answering.

Summary

Field Value
Title A comparative evaluation of chain-of-thought-based prompt engineering techniques for medical question answering
URL https://www.sciencedirect.com/science/article/pii/S0010482525009655
Date accessed 2026-03-25
Publication date 2025
Author(s) Not extracted from search results
Publication Computers in Biology and Medicine (ScienceDirect)

Selection Decision

Included in evidence base: Yes

Rationale: Provides domain-specific evidence that advanced CoT variants can reduce performance. Found that Interactive CoT's metacognitive approach often resulted in lower performance, and that CoT boosted overconfidence alongside accuracy gains in medical contexts.