R0002/2026-03-13/C010 — ACH Matrix¶
Matrix¶
| H1: No combination exists | H2: Partial combinations exist | H3: Similar combination exists | |
|---|---|---|---|
| SRC01-E01: JMIR clinical domain only | + | N/A | N/A |
| SRC02-E01: Frontiers medical domain only | + | N/A | N/A |
| S01 null result: IC + scientific search | + | N/A | N/A |
| S02 null result: ICD 203 + CONSORT/ROBIS | + | N/A | N/A |
| S03 null result: LLM + analytic techniques | + | N/A | N/A |
| S04 null result: AI prompt cross-domain | + | N/A | N/A |
Legend:
- ++ Strongly supports
- + Supports
- -- Strongly contradicts
- - Contradicts
- N/A Not applicable to this hypothesis
Diagnosticity Analysis¶
Most Diagnostic Evidence¶
| Evidence ID | Why Diagnostic |
|---|---|
| S02 null result | The most targeted search (ICD 203 + CONSORT + ROBIS + prompt) returned only IC-domain results. If a cross-domain combination existed, this search was most likely to find it. Its null result is the most diagnostic evidence supporting H1. |
Least Diagnostic Evidence¶
| Evidence ID | Why Non-Diagnostic |
|---|---|
| SRC01-E01, SRC02-E01 | These sources document domain-specific work. Their absence of cross-domain content is expected and does not strongly discriminate between hypotheses -- individual papers are not expected to survey all possible combinations. |
Outcome¶
Hypothesis supported: H1 -- No evidence found of a prior systematic combination. Four independent search strategies converged on the same null result. However, this is supported by absence of evidence, not positive confirmation.
Hypotheses eliminated: None -- universal negatives cannot be conclusively proven. H2 and H3 are not supported but cannot be definitively eliminated.
Hypotheses inconclusive: H2 and H3 -- Not supported by any evidence found, but the search was limited to web-accessible sources. Both remain theoretically possible.
Special Note: Conflict of Interest¶
The researcher is the author of the hybrid prompt and has a direct interest in the novelty claim. This is the highest-risk claim for confirmation bias. The null result should be interpreted cautiously, and the claim should use hedged language ("to our knowledge") rather than an absolute negative.